Distillation has long been recognized as the most reliable method to generate sterile pyrogen-free water. This natural liquid-vapor-liquid phase process consistently remove impurities from water without the use of...
Double Pass Reverse Osmosis
Reverse osmosis (RO) is a technology based on a semi-permeable membrane that is permeable to the water but impermeabile to other substances as salts, endotoxins and bacteria.
Reverse osmosis membrane salt removal is over (>99,5%), the double pass RO configuration is able to guarantee with high reliability the compliance with the Pharmacopoeias requirements.
Specifications
Pharmaceutical Water
Reverse osmosis double pass is widely used for the production of non-compendial and compendial Purified Water (PW) meeting the USP and European Pharmacopoeia requirements. More than 200 ELETTRACQUA Reverse Osmosis systems have been successfully validated across the world.
Skid construction features
Each ELETTRACQUA system is customized to meet our customers requirements, starting for example from room lay out to have the best installation solution.
- Frame: AISI 304
- Piping and fittings: AISI 316L ASME BPE
- Connections: Tri-clamp
- Membrane Housings: AISI 316L
- Valves: AISI 316L
Compliance
- CGMP
- USP PW
- EU Pharmacopoeia
- ISPE Baseline Guide
- GAMP
Sanitization
ELETTRACQUA Reverse osmosis systems can be supplied with different sanitization configurations:
- Chemical sanitization
- Hot water sanitization
Hot Water sanitization advantages
Elettracqua high temperature RO are sanitized with hot water (> 80°C), having several advantages compared to chemical sanitization:
- Sanitization process fully automated managed by PLC with continuous monitoring of sanitization temperatures
- Simplified validation of the thermal process
- Reliable process
- No need to prove the chemical rinse out
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